Table 5 Functional verification between ELM functional classes and the respective associated sequences.
ELM | Sequences | ||
|---|---|---|---|
Functional class | GO category | PDB id | GO category |
LIG_14-3-3_2 | Binding | 2O34A, 2FPHX, 1NAR0, 2DDXA | Binding, catalytic activity |
LIG_PP1 | Binding, enzyme regulator activity | 2HHPA, 2HFKA, 1D3YA, 1OI7A, 1ZY7A, 2B18A, 2F2HA, 2GZQA | Binding, catalytic activity, transporter activity, transcription regulator activity |
LIG_PP2B_1 | Binding, catalytic activity | 1ES5A, 1T8TA, 1EZWA, 1V5VA | Catalytic activity |
LIG_MAPK_1 | Binding | 1B43A, 1NSZA, 2GAKA, 2O34A, 1VPDA, 2NQTA | Binding, catalytic activity, |
LIG_SCF-TrCP1_1 | Binding, catalytic activity | 1B43A, 1Y8TA, 1M4LA, 2IDLA | Binding, catalytic activity |
LIG_14-3-3_3 | Binding | 2IDLA, 2HHPA, 2O34A, 1UG6A, 2C0HA, 1B12A, 1O54A, 2FPHX, 1GNLA, 2FMPA, 1D3GA, 2ES4D, 2DXQA, 2A67A, 2G0WA, 1PO5A, 1Q74A, 1CNV0, 1JNDA, 1KMVA, 2JG0A, 7A3HA | Binding, catalytic activity |
LIG_EH1_1 | Binding | 1B12A, 2C0HA, 1WDPA, 2CK3H, 1O54A, 2HHPA, 1R5YA, 2D0OA, 1USGA, 2DG1A, 1O2DA, 1YACA, 1RYIA, 1VZIA, 1NAR0, 2DSKA, 1NTHA, 2AFWA, 2C61A, 1D3GA, 1NNWA, 2NX9A, 1X13A, 2A67A, 1C8XA, 2AEEA, 1YDYA, 2GAKA | Binding, catalytic activity |
LIG_BRCT_BRCA1_1 | Binding | 1FSGA, 1OQ1A, 2FPQA, 1ZMTA, 2AZ4A, 1NOFA, 1UEKA, 2HSIA | Binding, catalytic activity |
LIG_NRBOX | Binding | 1M4LA, 2NT0A, 2NX9A, 1VLRA, 2DJFA, 1DQPA, 1G2QA, 1J2RA, 1NF9A, 1ITXA, 2JE8A, 1B25A, 1CNV0, 1NAR0, 2DSKA, 2CK3H, 2IACA, 1FSGA, 1VJPA, 1NTHA, 2HSIA | Binding, catalytic activity |
LIG_CORNRBOX | Binding | 1O54A, 2C61A, 1C8XA, 1LBVA | Binding, catalytic activity, transporter activity |