Table 2 Some associations masked by unfaithfulness from the WTCCC data set.
From: A hidden two-locus disease association pattern in genome-wide association studies
Disease | SNP X p | Single-locus P-value | SNP X q | Single-locus P-value | Chr | Gene | Unfaithfulness P-value |
|---|---|---|---|---|---|---|---|
BD | rs668860 | 0.053 | rs10873672 | 0.245 | 1 | MCOLN2 | 4.885 × 10-15 |
|  | rs668860 | 0.053 | rs6691970 | 0.216 | 1 | MCOLN2 | 6.217 × 10-15 |
CAD | rs7162070 | 0.867 | rs16969478 | 0.160 | 15 | FSIP1 | 5.551 × 10-15 |
|  | rs1876853 | 0.903 | rs16969478 | 0.160 | 15 | FSIP1 | 2.310 × 10-13 |
|  | rs8029602 | 0.853 | rs16969478 | 0.160 | 15 | FSIP1 | 5.274 × 10-14 |
|  | rs16969475 | 0.823 | rs16969478 | 0.160 | 15 | FSIP1 | 1.259 × 10-13 |
T1D | rs1058318 | 0.074 | rs2252745 | 0.840 | 6 | GNL1, PPP1R10 | 1.326 × 10-12 |
HT | rs2300390 | 0.460 | rs12482676 | 0.061 | 21 | RCAN1 | 2.442 × 10-15 |