Skip to main content

Table 12 What is the effect on FunFOLD performance if the native structures are used for each target? A repeat comparison of FunFOLD performance versus the top 3 groups for at CASP9 using partial binding site definitions.

From: FunFOLD: an improved automated method for the prediction of ligand binding residues using 3D models of proteins

Group ID N Mean score for group Mean score for FunFOLD Difference in mean score Mean Z-score for group Mean Z-score for FunFOLD P-value
(raw score)
P-value
(Z-score)
1 - p-value
(raw score)
1 - p-value
(Z-score)
   MCC BDT MCC BDT MCC BDT MCC BDT MCC BDT MCC BDT MCC BDT MCC BDT MCC BDT
FN035 22 0.714 0.644 0.621 0.541 -0.092 -0.103 0.627 0.627 0.387 0.197 0.649 0.869 0.784 0.889 0.351 0.131 0.216 0.111
FN096 25 0.696 0.620 0.617 0.534 -0.079 -0.086 0.555 0.499 0.404 0.250 0.674 0.850 0.594 0.771 0.326 0.150 0.406 0.229
FN339 25 0.668 0.606 0.617 0.534 -0.051 -0.072 0.462 0.482 0.404 0.250 0.614 0.837 0.500 0.771 0.386 0.163 0.500 0.229