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Table 13 What is the effect on FunFOLD performance if the native structures are used for each target? A repeat comparison of FunFOLD performance versus the top 3 groups for at CASP9 using extended binding site definitions.

From: FunFOLD: an improved automated method for the prediction of ligand binding residues using 3D models of proteins

Group ID N Mean score for group Mean score for FunFOLD Difference in mean score Mean Z-score for group Mean Z-score for FunFOLD P-value
(raw score)
P-value
(Z-score)
1 - p-value
(raw score)
1 - p-value
(Z-score)
   MCC BDT MCC BDT MCC BDT MCC BDT MCC BDT MCC BDT MCC BDT MCC BDT MCC BDT
FN035 21 0.635 0.538 0.585 0.520 -0.050 -0.018 0.528 0.567 0.465 0.462 0.684 0.620 0.636 0.695 0.316 0.380 0.364 0.305
FN096 24 0.632 0.526 0.585 0.516 -0.046 -0.010 0.468 0.343 0.472 0.484 0.678 0.605 0.450 0.406 0.322 0.395 0.550 0.594
FN339 24 0.606 0.501 0.585 0.516 -0.021 -0.015 0.426 0.302 0.472 0.484 0.614 0.439 0.386 0.332 0.386 0.561 0.614 0.668