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Table 3 The mean MCC and BDT raw scores and Z-scores obtained by FunFOLD are compared with those obtained by each CASP8 function prediction group - as in Table 1 except for CASP8 targets containing non-metal ligands or metal and non-metal ligands in the same binding site.

From: FunFOLD: an improved automated method for the prediction of ligand binding residues using 3D models of proteins

Group ID N Mean score for group Mean score for FunFOLD Increase in mean score Mean Z-score for group Mean Z-score for FunFOLD P-value
(raw score)
P-value
(Z-score)
1 - p-value
(raw score)
1 - p-value
(Z-score)
   MCC BDT MCC BDT MCC BDT MCC BDT MCC BDT MCC BDT MCC BDT MCC BDT MCC BDT
FN407 11 0.774 0.700 0.752 0.690 -0.022 -0.010 1.156 1.100 1.061 1.018 0.681 0.517 0.681 0.449 0.319 0.483 0.319 0.551
FN293 10 0.778 0.703 0.771 0.722 -0.006 0.020 1.101 0.008 1.074 1.077 0.423 0.278 0.423 0.313 0.577 0.722 0.577 0.688
FN163 11 0.723 0.705 0.752 0.690 0.029 -0.015 0.966 1.072 1.061 1.018 0.183 0.382 0.183 0.416 0.817 0.618 0.817 0.584
FN057 11 0.646 0.633 0.752 0.690 0.160 0.058 0.738 0.828 1.061 1.018 0.139 0.382 0.120 0.381 0.861 0.618 0.880 0.618
FN417 11 0.583 0.528 0.752 0.690 0.169 0.162 0.541 0.458 1.061 1.018 0.012 0.021 0.012 0.042 0.988 0.979 0.988 0.958
FN450 10 0.442 0.418 0.771 0.722 0.330 0.305 0.077 0.038 1.074 1.077 0.002 0.003 0.002 0.003 0.988 0.997 0.998 0.997
FN325 11 0.389 0.360 0.752 0.690 0.362 0.331 -0.076 -0.102 1.061 1.018 0.003 0.002 0.003 0.002 0.987 0.998 0.997 0.998
FN034 10 0.317 0.292 0.743 0.687 0.426 0.395 -0.026 -0.362 1.031 0.972 0.003 0.005 0.006 0.005 0.994 0.995 0.994 0.995
FN108 11 0.156 0.185 0.752 0.690 0.596 0.505 -0.819 -0.750 1.061 1.018 0.000 0.000 0.000 0.000 1.000 1.000 1.000 1.000
FN242 11 0.109 0.101 0.752 0.690 0.643 0.590 -0.965 -1.069 1.061 1.018 0.000 0.000 0.000 0.000 1.000 1.000 1.000 1.000
FN086 11 0.074 0.118 0.752 0.690 0.678 0.572 -1.061 -0.990 1.061 1.018 0.000 0.000 0.000 0.000 1.000 1.000 1.000 1.000
FN105 11 0.020 0.063 0.752 0.690 0.731 0.628 -1.260 -1.207 1.061 1.018 0.000 0.000 0.000 0.000 1.000 1.000 1.000 1.000