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Table 8 The mean MCC and BDT raw scores and Z-scores obtained by FunFOLD are compared with those obtained by the top CASP9 function prediction groups - as in Table 6 except for CASP9 targets containing non-metal ligand s or metal and non-metal ligand s in the same binding site.

From: FunFOLD: an improved automated method for the prediction of ligand binding residues using 3D models of proteins

Group ID N Mean score for group Mean score for FunFOLD Difference in mean score Mean Z-score for group Mean Z-score for FunFOLD P-value
(raw score)
P-value
(Z-score)
1 - p-value
(raw score)
1 - p-value
(Z-score)
   MCC BDT MCC BDT MCC BDT MCC BDT MCC BDT MCC BDT MCC BDT MCC BDT MCC BDT
FN096 18 0.644 0.545 0.536 0.465 -0.108 -0.081 0.566 0.416 0.140 0.194 0.941 0.848 0.877 0.710 0.059 0.152 0.123 0.290
FN339 18 0.620 0.511 0.536 0.465 -0.084 -0.046 0.505 0.298 0.140 0.194 0.790 0.551 0.776 0.517 0.210 0.449 0.224 0.483
FN035 18 0.613 0.518 0.536 0.465 -0.076 -0.053 0.503 0.544 0.140 0.194 0.888 0.909 0.888 0.909 0.112 0.091 0.112 0.091
FN242 17 0.609 0.526 0.533 0.467 -0.076 -0.059 0.447 0.417 0.106 0.188 0.789 0.510 0.803 0.612 0.211 0.490 0.197 0.388
FN315 18 0.601 0.503 0.536 0.465 -0.065 -0.038 0.376 0.377 0.140 0.194 0.710 0.779 0.665 0.752 0.290 0.221 0.335 0.248
FN104 18 0.571 0.495 0.536 0.465 -0.035 -0.030 0.180 0.192 0.140 0.194 0.776 0.710 0.746 0.567 0.224 0.290 0.254 0.433
FN110 18 0.569 0.515 0.536 0.465 -0.034 -0.050 0.144 0.297 0.140 0.194 0.416 0.617 0.290 0.500 0.584 0.383 0.710 0.500
FN094 18 0.526 0.468 0.536 0.465 0.010 -0.004 0.119 0.128 0.140 0.194 0.449 0.594 0.469 0.594 0.551 0.406 0.531 0.406
FN236 18 0.499 0.437 0.536 0.465 0.036 0.028 -0.017 -0.135 0.140 0.194 0.295 0.294 0.356 0.243 0.705 0.706 0.644 0.757
FN452 17 0.520 0.423 0.533 0.467 0.013 0.044 -0.065 -0.220 0.106 0.188 0.399 0.112 0.335 0.078 0.601 0.888 0.665 0.922
FN114 18 0.520 0.452 0.536 0.465 0.016 0.013 -0.092 -0.165 0.140 0.194 0.370 0.285 0.285 0.197 0.630 0.715 0.715 0.803
FN425 18 0.473 0.397 0.536 0.467 0.063 0.069 -0.150 -0.232 0.121 0.203 0.173 0.084 0.143 0.129 0.827 0.916 0.857 0.871
FN017 18 0.464 0.414 0.536 0.465 0.072 0.051 -0.303 -0.225 0.140 0.194 0.114 0.114 0.084 0.059 0.886 0.886 0.916 0.941
FN415 18 0.457 0.408 0.536 0.465 0.079 0.057 -0.401 -0.356 0.140 0.194 0.071 0.084 0.049 0.030 0.929 0.916 0.951 0.970
FN057 18 0.445 0.413 0.536 0.465 0.091 0.052 -0.538 -0.274 0.140 0.194 0.059 0.209 0.017 0.142 0.941 0.791 0.983 0.858
FN072 18 0.439 0.401 0.536 0.465 0.097 0.064 -0.590 -0.381 0.140 0.194 0.052 0.106 0.016 0.071 0.948 0.894 0.984 0.929
FN113 18 0.447 0.340 0.536 0.465 0.089 0.125 -0.810 -0.878 0.140 0.194 0.054 0.003 0.012 0.003 0.946 0.997 0.988 0.997