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Figure 2 | BMC Bioinformatics

Figure 2

From: CASCADE_SCAN: mining signal transduction network from high-throughput data based on steepest descent method

Figure 2

The pheromone response pathway. (A) The pheromone response pathway obtained from KEGG. The darker nodes indicate nodes in the KEGG pheromone response pathway but not detected by CASCADE_SCAN. (B) The CASCADE_SCAN output for the pheromone response pathway (74% recall and 82% precision). The darker nodes indicate detected by CASCADE_SCAN but not in the KEGG pheromone response pathway. (PPI score threshold: 0.800, credible PPI score threshold: 0.980, DFS path length: 2, seed proteins: CDC24, DIG1, FAR1 and STE4).

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