Figure 2From: CASCADE_SCAN: mining signal transduction network from high-throughput data based on steepest descent methodThe pheromone response pathway. (A) The pheromone response pathway obtained from KEGG. The darker nodes indicate nodes in the KEGG pheromone response pathway but not detected by CASCADE_SCAN. (B) The CASCADE_SCAN output for the pheromone response pathway (74% recall and 82% precision). The darker nodes indicate detected by CASCADE_SCAN but not in the KEGG pheromone response pathway. (PPI score threshold: 0.800, credible PPI score threshold: 0.980, DFS path length: 2, seed proteins: CDC24, DIG1, FAR1 and STE4).Back to article page