Figure 4
From: An analysis of single amino acid repeats as use case for application specific background models
Enrichment of single amino acid repeats in signal peptides. We compare the SAAR frequency in the whole protein (including the signal peptide) to the SAAR frequency in the mature parts. For a standardized display, we consider ratios of observed SAAR counts versus counts predicted by the background model. We plot the difference between these ratios for whole and mature proteins in terms of model standard deviations (y-axis), and test for positive values. For significant enrichment (p < 5%) the p-values are printed next to the symbol. Median data are shown for a selection of hydrophobic amino acids (A, F, I, L, and V, as indicated by symbols) and repeat lengths from five to ten (x-axis).