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Table 1 Point mutation statistics for the reference strict phylogeny

From: Rebooting the human mitochondrial phylogeny: an automated and scalable methodology with expert knowledge

Mutation type

Conserved

Back-mutation

Conserved B-M

Remaining

Total

Unambiguous

27489

16915

4672

6976

46708

Ungapped

22158

6825

3365

2159

27777

Ambiguous

19960

0

0

1232

21192

Total

47449

16915

4672

8208

67900

  1. Mutations are classified and counted according to their qualitative properties. Row categories separate perfectly defined mutations from those that involve ambiguous positions of some sort; "ungapped" unambiguous substitutions (mutations that do not involve gaps, i.e., indels) are given a separate category as well (Total = Ambiguous + Unambiguous, Unambiguous ≥ Ungapped). Columns relate mutations with alignment conservation information (95% threshold) and evolutionary history from the root of the tree to several types of significant events (Total = Conserved + Back-mutation - Conserved B-M + Remaining).