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Table 1 Test cases for validation and assessment of MimoPro

From: MimoPro: a more efficient Web-based tool for epitope prediction using phage display libraries

PDB_ID antibody antigen Mimotopes# Ref
1JRH A6, IgG1 IFNgammaR 59 × 5 [37]
1BJ1 rhuMAb vascular endothelial growth factor 36 × 6, 3 × 5, 2 × 4 [38]
1G9M 17b gp120 10 × 14, 1 × 12 [43]
1E6J 13B5 p24 14 × 14, 2 × 7 [43]
1N8Z Herceptin Her-2 5 × 12 [44]
1N8Z* Herceptin Her-2 8 × 12 [39]
1IQD BO2C11 Coagulation factor VIII 27 × 12 [45]
1YY9 Cetuximab Epidermal Growth Factor Receptor 3 × 10 [44]
2ADF 82D6A3, IgG human von Willebrand factor (vWF) 2 × 15, 3 × 6 [46]
1ZTX E16 West Nile Virus envelope glycoprotein(WNV E) 3 × 13, 19 × 14 [47]
3IU3 basiliximab Interleukin-2 receptor subunit alpha 6 × 9 MS00013$
2GHW 80R Spike glycoprotein 9 × 16, 11 × 15, 17 × 14, 4 × 13 MS00059$
2NY7 B12 Surface protein gp120 17 × 14, 1 × 10, 1 × 13 MS00056$
Protein-protein interaction   
1AVZ Fyn SH3 domain Nef Bovine 8 × 11, 10 × 12 [48]
1HX1 Hsc70 Bag chaperone regulator 8 × 15 [49]
1SQ0 Platelet glycoprotein Ib alpha chain von Willebrand factor (vWF) 3 × 11 MS00465$
1MQ8 ICAM-1 Integrin alpha-L beta-2 1 × 14 MS01004$
1II4 FGFR-2 HBGF-2 30 × 7 MS01105/MS01110/MS01115$
  1. # Number of peptides x peptide length
  2. * 1N8Z* shares the same crystal complex with 1N8Z in PDB database.
  3. $ These cases are entries in a newly released database MimoDB [36] located at http://immunet.cn/mimodb/index.html.