Figure 2

Characteristics comparison between heme binding and non-binding residues. (a) Interface propensity, (b) Evolutionary conservation, (c) Solvent accessibility, (d) Depth, (e) Protrusion, (f) Spatial clustering of binding residues. The distributions of (b)-(f) were obtained by dividing all the residues of main dataset into different brackets according to their attribute values and calculating the percentages of binding and non-binding residues in each bracket.