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Table 2 The big scale and final selection orders of the real linkage data analysis

From: Network-based group variable selection for detecting expression quantitative trait loci (eQTL)

Network 1 Marker sets 1 Marker sets 2
Trt/Gene Big Scale NGVS Big Scale SinTrt Final Selection NGVS Big Scale NGVS Big Scale SinTrt Final Selection NGVS
1/Cldn4 2, 16, 11 4, 2, 7 15, 16, 18, 161, 114 3, 27, 20 23, 5, 3 15, 16, 17, 157, 114
2/Lor 3, 2, 11 10, 1, 4 33, 16, 17, 18, 113 3, 6, 18 18, 14, 13 16, 17, 33, 107, 14
3/Doc2b 2, 6, 7 11, 5, 1 16, 18, 17, 70, 80 3, 13, 11 13, 3, 23 16, 17, 81, 68, 9
4/F2rl2 2, 8, 6 5, 6, 11 15, 17, 30, 93, 71 3, 14, 18 14, 3, 26 15, 17, 85, 107, 105
5/St8sia5 10, 18, 2 4, 6, 5 107, 106, 180, 16, 70 3, 18, 31 18, 14, 32 16, 107, 106, 180, 100
6/Nptx1 2, 6, 7 10, 4, 5 16, 17, 68, 80, 70 3, 6, 11 3, 13, 18 16, 17, 32, 68, 70
7/Kcna2 2, 6, 18 5, 1, 4 16, 68, 17, 178, 70 3, 31, 6 13, 14, 3 16, 17, 178, 180, 33
8/Rnf17 18, 2, 1 5, 16, 1 183, 16, 9, 180, 184 3, 32, 1 3, 10, 1 16, 17, 14, 183, 2
9/Ankrd24 2, 3, 11 4, 1, 2 16, 17, 33, 36, 120 3, 6, 13 13, 3, 14 16, 17, 33, 81, 119
10/Gstm7 2, 4, 11 5, 4, 12 16, 45, 113, 128, 17 3, 8, 27 18, 8, 3 16, 45, 17, 157, 113
11/Tcfcp2l3 2, 12, 6 10, 5, 7 16, 17, 122, 68, 70 3, 18, 21 18, 13, 23 16, 17, 15, 107, 122
12/Stmn3 3, 6, 7 7, 11, 10 36, 68, 81, 80, 32 3, 6, 13 13, 18, 3 16, 17, 32, 81, 36
13/Rasgrf1 13, 9, 2 4, 5, 13 131, 94, 17, 15, 96 3, 17, 22 5, 17, 8 15, 101, 131, 17, 102
14/Sfrp1 10, 3, 2 10, 4, 5 107, 110, 31, 16, 17 3, 18, 27 18, 3, 8 16, 107, 17, 157, 45
15/Ergic1 2, 3, 11 11, 4, 10 16, 17, 30, 33, 113 3, 6, 22 3, 18, 13 16, 17, 33, 131, 135
16/Cd33 9, 4, 13 4, 6, 5 96, 44, 131, 15, 41 8, 3, 17 14, 8, 16 44, 15, 41, 43, 101
Network 2 Marker sets 1 Marker sets 2
Trt/Gene Big Scale NGVS Big Scale SinTrt Final Selection NGVS Big Scale NGVS Big Scale SinTrt Final Selection NGVS
1/Calcrl 9, 8, 12 4, 18, 1 101, 85, 122, 178, 121 14, 17,31 31, 2, 8 85, 101, 178, 16, 13
2/Ccr5 3, 2, 1 7, 1, 6 34, 15, 16, 35, 33 3, 6, 2 13, 2, 3 15, 16, 34, 10, 154
3/Rgs6 10, 3, 1 4, 10, 8 105, 107, 103, 37, 2 18, 23, 1 18, 9, 27 105,141, 107, 103, 106
4/Rps6ka4 2, 4, 12 6, 5, 9 15, 30, 16, 27, 14 3, 5, 17 5, 17, 3 15, 16, 30, 14, 28
5/Cysltr1 5, 3, 6 4, 5, 13 61, 57, 58, 33, 68 6, 17, 23 8, 13, 23 33, 34, 32, 100, 101
6/P2ry12 6, 3, 18 4, 8, 6 68, 31, 178, 40, 85 6, 31, 3 14, 25, 8 31, 178, 16, 68, 13
7/Rassf1 6, 3, 10 10, 11, 4 70, 68, 32, 107, 120 3, 6, 11 3, 18, 5 16, 14, 17, 32, 70
8/Rgs3 9, 2, 13 11, 5, 12 101, 16, 30, 26, 95 17, 3, 14 17, 3, 2 101, 16, 100, 85, 135
9/Apln 6, 2, 3 10, 7, 6 68, 16, 17, 70, 71 3, 11, 18 18, 13, 3 16, 68, 17, 70, 107
10/Dok4 15, 9, 6 15, 11, 4 154, 153, 152, 96, 68 26, 3, 17 26, 13, 5 154, 153, 152, 15, 101
11/Lphn1 15, 6, 8 8, 6, 10 154, 71, 156, 68, 88 3, 26, 14 14, 26, 6 16, 154, 156, 85, 17
12/Kcnq1 9, 15, 3 5, 3, 7 95, 157, 40, 39, 108 27, 3, 7 7, 27, 3 157, 16, 40, 13, 17
13/Gabbr1 4, 2, 13 4, 13, 12 44, 16, 30, 41, 45 3, 17, 14 8, 5, 3 16, 100, 85, 44, 41
14/Gnai1 9, 17, 6 9, 19, 17 101, 172, 170, 70, 51 17, 5, 9 17, 29,33 101, 30, 26, 27, 29
15/Rgs3(2) 18, 6, 12 5, 10, 1 184, 68, 70, 178, 179 31, 32,11 14, 18,17 178, 184, 68, 70, 85
16/1200007
D18Rik
6, 10, 3 10, 5, 1 68, 108, 107, 109, 70 23, 3, 18 18, 23,13 140, 16, 17, 15, 107
17/Cxcr3 6, 13, 14 6, 11, 4 68, 131, 135, 149, 15 3, 31, 22 13, 3, 11 15, 17, 178, 131, 135
  1. The co-expression network 1 was constructed by 16 GPCR traits and a cutoff of 0.8. The co-expression network 2 was constructed by 17 GPCR traits shared by two datasets and a cutoff of 0.4 was used. Marker set 1 and 2 denotes respectively loci within one chromosome and loci within the boundaries where significant correlation decrease happens were grouped as one markerset. Numbers in big scale orders of NGVS and Single trait selection represent the corresponding marker set numbers, while final selection orders of NGVS represent the marker numbers.