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Table 1 The distribution of methylation proportion by patient subgroup (Group 1, Group 2), in the simulation study

From: Modeling measurement error in tumor characterization studies

  Bernoulli
Proportion
1
Beta
distribution
2
   
   Mean Var   
Scenario (Group 1,
Group 2)
(Group 1,
Group 2)
(Group 1,
Group 2)
Difference in
Overall Means
Difference in
Overall Vars 3
a.i (1,1) (0.2, 0.27) (0.01, 0.01) 0.07 0
a.ii    (0.04, 0.04) 0.07 0
a.iii    (0.01, 0.04) 0.07 0.3
b.i   (0.4, 0.47) (0.01, 0.01) 0.07 0
b.ii    (0.04, 0.04) 0.07 0
b.iii    (0.01, 0.04) 0.07 0.3
c.i (0.5,0.7) (0.4, 0.47) (0.01, 0.01) 0.13 0.01
c.ii    (0.04, 0.04) 0.13 0.01
c.iii    (0.01, 0.04) 0.13 0.02
  1. 1 The probability that the true methylation proportion is positive
  2. 2 Distribution of the true methylation proportion in methylated tumors
  3. 3 Estimated from the data.