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Table 3 Comparison of correlations (r) between MAQC2 RNA-Seq data and other platforms.

From: Bias detection and correction in RNA-Sequencing data

Platform1 Platform2 Sample Log fold changes Original r r after GAM Correction %Relative improvement
RNA-Seq Taqman Brain (0, 0.326] 0.749 0.747 -0.3
    (0.326, 0.731] 0.664 0.699 5.3
    (0.731, 2.1] 0.655 0.807 23.2
    Overall 0.69 0.754 9.3
RNA-Seq Taqman UHR (0, 0.368] 0.778 0.774 -0.5
    (0.368, 0.753] 0.776 0.79 1.8
    (0.753, 1.78] 0.704 0.724 2.8
    Overall 0.748 0.763 2
RNA-Seq QuantiGene Brain (0, 0.3] 0.833 0.823 -1.2
    (0.3, 0.743] 0.659 0.721 9.4
    (0.743, 1.69] 0.647 0.738 14.1
    Overall 0.725 0.766 5.7
RNA-Seq QuantiGene UHR (0, 0.375] 0.832 0.839 0.8
    (0.375, 0.793] 0.811 0.759 -6.4
    (0.793, 1.78] 0.632 0.692 9.5
    Overall 0.771 0.777 0.8
  1. Gene expression levels from Taqman RT-PCR or QuantiGene platforms are compared with RNA-Seq data, before and after bias correction by GAM.