miRTar: an integrated system for identifying miRNA-target interactions in human

BMC Bioinformatics

Table 1 The comparisons of miRNA target prediction tools.

Features	miRTar	DIANA-microT/miRPath[47, 68]	EIMMO[6]	miRU[20]	RNAhybrid[11]	STarMir[23]	RNA22[22]	MMIA[24]
Species	Human	Human and mouse	Vertebrates, nematode, fly	Plants	Human, nematodes, flies	-	Vertebrates, nematode, fly	Human
* 1 to 1	+	+	+	-	+	+	+	-
* 1 to N	+	1 to All genes	+	-	+	+	-	+
* N to 1	+	-	+	-	+	+	-	-
* N to M	+	-	+	-	+	+	-	+
* All to M	+	All miRNAs to 1	+	-	-	-	-	-
* 1 to KEGG	+	+	-	-	-	-	-	-
miRNA targets on alternatively splicing exon	+	-	-	-	-	-	-	-
miRNA targets from mRNA	3'UTR, CDS, and 5'UTR	3'UTR	3'UTR	3'UTR, CDS, and 5'UTR	3'UTR	3'UTR, CDS, and 5'UTR	3'UTR, CDS, and 5'UTR	3'UTR
Known miRNAs	miRBase V15	-	miRBase V12	-	-	-	-	-
Accessibility of target site	+	-	-	-	-	Sfold	-	-
Conservation of target site	+	+	+	+	-	-	-	-
Expression profile of miRNA	-	-	-	-	-	-	-	+
Expression profile of target	-	-	+	-	-	-	-	+

* 1 to 1 means the relation of one miRNA and one gene; 1 to N means the relation of one miRNA to multiple interesting genes; N to 1 means the relation of N miRNAs and one gene; N to M means the relation of N miRNAs and M genes; All to M means the relation of all miRNAs and M genes; 1 to KEGG means the relation of one miRNA and the genes of the selected KEGG map.

ISSN: 1471-2105