R
_{
0,E. coli
}

0.4

μm

E. coli radius

L
_{
E. coli
}

2.3

μm

Representative E. coli length

A
_{
E. coli
}

5.8

μm^{2}

E. coli membrane area (for the above length)

V
_{
E. coli
}

1.0

fL

E. coli volume (for the above length)

O
_{
T
}

1

(copy number)

operator molecular content

k
_{
sMR
}

0.23

nM·min^{1}

lacI transcription rate

k
_{
sR
}

15

min^{1}

LacI monomer translation rate constant

k
_{
2R
}

50

nM^{1}·min^{1}

LacI dimerization rate constant

k
_{
2R
}

10^{3}

min^{1}

LacI dimer dissociation rate constant

k
_{
r
}

960

nM^{1}·min^{1}

association rate constant for repression

k
_{
r
}

2.4

min^{1}

dissociation rate constant for repression

k
_{
dr1
}

3·10^{7}

nM^{2}·min^{1}

association rate constant for 1^{st} derepression mechanism

k
_{
dr1
}

12

min^{1}

dissociation rate constant for 1^{st} derepression mechanism

k
_{
dr2
}

3·10^{7}

nM^{2}·min^{1}

association rate constant for 2^{nd} derepression mechanism

k
_{
dr2
}

4.8·10^{3}

nM^{1}·min^{1}

dissociation rate constant for 2^{nd} derepression mechanism

k
_{
s1MY
}

0.5

min^{1}

lacY transcription rate constant

k
_{
s0MY
}

0.01

min^{1}

leak lacY transcription rate constant

k
_{
sY
}

30

min^{1}

lacY translation rate constant

k
_{
p
}

0.12

nM^{1}·min^{1}

LacYinducer association rate constant

k
_{
p
}

0.1

min^{1}

LacYinducer dissociation rate constant

k
_{
ft
}

6·10^{4}

min^{1}

TMG facilitated transport constant

h
_{
t
}

1.55·10^{6}

dm·min^{1}

TMG passive diffusion permeability constant

λ_{
MR
}

0.462

min^{1}

lacI mRNA degradation constant

λ_{
MY
}

0.462

min^{1}

lacY mRNA degradation constant

λ_{
R
}

0.2

min^{1}

LacI monomer degradation constant

λ_{
R2
}

0.2

min^{1}

LacI dimer degradation constant

λ_{
Y
}

0.2

min^{1}

LacY degradation constant

λ_{
YIex
}

0.2

min^{1}

LacYinducer degradation constant

λ_{
I2R2
}

0.2

min^{1}

repressorinducer degradation constant

g

0.0231

(min^{1})

cell growth rate parameter

n
_{
d
}

25

(dim/less)

division propensity sharpness exponent

V
_{
d,crit
}

15

(fL)

critical volume for division

q

80

(dim/less)

beta distribution sharpness exponent

n
_{
s
}

25

(dim/less)

DNA duplication propensity sharpness exponent

V
_{
s,crit
}

10

(fL)

critical volume for DNA duplication
