|
Evolutionary conservation score
|
Sequence entropy
|
---|
|
Ab+
|
Ab-
|
Ab+
|
Ab-
|
Hot spotsa
|
4.46
|
5.63
|
45.84
|
35.14
|
Non-hot spotsb
|
4.08
|
4.28
|
47.87
|
44.59
|
P-value
|
0.14
|
10-4
|
0.36
|
1.1 × 10-3
|
- Ab+ represents the database contains all complexes. Ab- represents the database excludes antigen-antibody complexes.
- a Mean value of hot spots.
- b Mean value of non-hot spots