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Table 1 Statistical analysis on evolutionary conservation score and sequence entropy between hot spots and non-hot spots

From: Rigorous assessment and integration of the sequence and structure based features to predict hot spots

  Evolutionary conservation score Sequence entropy
  Ab+ Ab- Ab+ Ab-
Hot spotsa 4.46 5.63 45.84 35.14
Non-hot spotsb 4.08 4.28 47.87 44.59
P-value 0.14 10-4 0.36 1.1 × 10-3
  1. Ab+ represents the database contains all complexes. Ab- represents the database excludes antigen-antibody complexes.
  2. a Mean value of hot spots.
  3. b Mean value of non-hot spots