Table 3 Percentage per base error rates in pyrosequencing reads before and after application of denoising algorithms

Divergent

0.4519%

0.1877%

0.8030%

0.7960%

0.1987%

Artificial

0.3678%

0.2469%

1.1733%

1.1891%

0.5605%

Even1

0.8767%

0.6381%

1.6990%

2.3572%

0.7585%

Even2

0.8870%

0.6456%

1.7906%

2.1536%

0.7986%

Even3

0.8446%

0.5935%

1.9895%

2.4594%

0.8033%

Uneven1

1.1852%

0.8998%

1.9687%

1.7756%

1.0897%

Uneven2

0.6713%

0.4851%

1.7549%

2.6078%

0.6646%

Uneven3

0.6560%

0.4344%

1.3370%

2.0822%

0.4913%

Titanium - σ _s = 0.1

0.4576%

0.1427%

0.5830%

0.7012%

0.3793%

Titanium - σ _s = 0.04

0.1325%