Figure 1

Screenshot of iCTNet. Genetic association data for more than 200 traits and diseases are available to download from the iCTNet database at a user-selectable significance threshold (-Log₁₀(p)). In addition, the user can choose to download disease-tissue, tissue-gene, and drug-gene interactions by simply ticking a checkbox. Protein-protein and protein-DNA interactions can also be downloaded at different degrees of separation (ds) or distance. Choosing a distance ds = 0 only downloads direct disease-gene associations, and any existing interaction among associated gene products (protein-protein). A distance ds = 1 will also include the first neighbors of genes directly associated.