Table 5 The top ten genes for 8 diseases with a reasonable training set
Prostate cancer | Â | Â | Gastric cancer | Â | Â |
|---|---|---|---|---|---|
CDKN2A(1029) | 210 | 1 | EGFR(1956) | 853 | 1 |
AKT1(207) | 1058 | 1 | AKT1(207) | 272 | 0 |
IGF1R(3480) | 152 | 1 | EXT1(2131) | 4 | 0 |
MSX1(4487) | 5 | 0 | FAS(355) | 180 | 0 |
PAX3(5077) | 2 | 0 | LRP5(4041) | 8 | 0 |
CCND1(595) | 372 | 1 | MSX1(4487) | 3 | 0 |
BRAF(673) | 22 | 1 | CCND1(595) | 250 | 1 |
TP53(7157) | 1378 | 1 | BRAF(673) | 32 | 1 |
WFS1(7466) | 0 | 0 | TP53(7157) | 1593 | 1 |
WT1(7490) | 37 | 1 | WFS1(7466) | 0 | 0 |
Colorectal cancer | Â | Â | Leukemia acute myeloid | Â | Â |
CDKN2A(1029) | 415 | 1 | AKT1(207) | 233 | 0 |
EXT1(2131) | 14 | 0 | FAS(355) | 136 | 0 |
IGF1R(3480) | 86 | 1 | KRAS(3845) | 457 | 1 |
SMAD4(4089) | 211 | 1 | LYN(4067) | 26 | 0 |
MLH1(4292) | 4064 | 1 | MYC(4609) | 381 | 0 |
PDGFRA(5156) | 19 | 1 | RAF1(5894) | 30 | 1 |
PDGFRB(5159) | 45 | 1 | STAT3(6774) | 95 | 0 |
BRAF(673) | 430 | 1 | STK11(6794) | 2 | 0 |
WFS1(7466) | 0 | 1 | BTK(695) | 6 | 0 |
WT1(7490) | 15 | 0 | TP53(7157) | 474 | 1 |
Diabetes mellitus | Â | Â | Breast cancer | Â | Â |
COL1A1(1277) | 4 | 0 | CDKN2A(1029) | 572 | 1 |
COL2A1(1280) | 6 | 0 | COL2A1(1280) | 9 | 0 |
CYP3A5(1577) | 5 | 0 | COL3A1(1281) | 1 | 0 |
EXT1(2131) | 20 | 1 | EXT1(2131) | 22 | 0 |
GHR(2690) | 49 | 0 | LRP5(4041) | 51 | 0 |
ABCC6(368) | 43 | 0 | MSX1(4487) | 10 | 0 |
LEP(3952) | 754 | 1 | PAX3(5077) | 6 | 0 |
LRP5(4041) | 58 | 0 | PITX2(5308) | 310 | 1 |
CACNA1S(779) | 4 | 0 | BRAF(673) | 37 | 1 |
ADIPOQ(9370) | 1635 | 1 | WFS1(7466) | 4 | 0 |
Alzheimer | Â | Â | Schizophrenia | Â | Â |
COL2A1(1280) | 0 | 0 | COL1A1(1277) | 0 | 0 |
CYP1B1(1545) | 0 | 0 | COL2A1(1280) | 0 | 0 |
EXT1(2131) | 4 | 1 | ATN1(1822) | 40 | 0 |
ALDH3A2(224) | 4 | 0 | EXT1(2131) | 20 | 0 |
APOE(348) | 4143 | 1 | FGFR3(2261) | 78 | 0 |
ABCC6(368) | 10 | 0 | GJB1(2705) | 0 | 0 |
LRP5(4041) | 3 | 0 | ABCC6(368) | 7 | 0 |
MAOA(4128) | 5 | 1 | LRP5(4041) | 4 | 0 |
PSEN2(5664) | 635 | 1 | PARK2(5071) | 1 | 0 |
WFS1(7466) | 1 | 0 | WFS1(7466) | 5 | 0 |