Specificity and spatial resolution of nucleosome predictions. (A) Fraction of predicted stable and non-stable nucleosomes considered significant at varying p-value cut-offs. A method that consistently produces smaller p-values for stable than for non-stable nucleosomes will result in a curve that gets closer to the top left corner than a method for which p-values and the stability of nucleosomes are unrelated. (B) Distance between nucleosome predictions from the third 10 M read sample and the location of stable nucleosomes. For each method observed distances are reported together with standard deviation of distances. A larger standard deviation corresponds to a lower resolution.