Table 4 Negated sentences for Parkinson's disease
From: BioN∅T: A searchable database of biomedical negated sentences
Gene | Sentence |
|---|---|
PINK1 | The phenotypic spectrum associated with PINK1-positive patients may be wider than previously reported. Polymorphisms of PINK1 do not appear to modulate risk of PD in our population. |
UCHL1 | UCHL1 genotyping is performed routinely in research settings; however, a UCHL1 laboratory test is not commercially available at this time. Given the lack of conclusive evidence supporting a strong association between UCHL1 polymorphisms and Parkinson's disease, it seems unlikely that UCHL1 population testing will be undertaken in the near future. The Venice criteria were developed by the Human Genome Epidemiology Network (HuGENet) Working Group to provide guidance in assessing the cumulative epidemiologic evidence of genetic association studies (104). |
LRRK2 | No association could be demonstrated. We have therefore no evidence for the existence of a common variant in LRRK2 that has a strong influence on Parkinson's disease risk. |