Figure 2

The comparison of power curves of F _Gen from unrestricted residual permutation versus other F -like test statistics. Only results from permutation combinations that can control prespecified CWER are used in this figure. The x-axis is the average power after analyzing 900 simulated data sets using F _Gen and 1,000 unrestricted residual permutations. The y-axis is the estimated power from other F-like test statistics and empirical gene-specific null distributions based on the appropriate permutation. The solid black line corresponds to F _Gen with unrestricted permutation, and this test always controls prespecified CWER."ce," all genes have common error; "gh," only between-gene heteroscedasticity exists; "wgh," only within-gene heteroscedasticity exists; "bgh," both between-gene and within gene heteroscedasticity exist; "res," restricted permutation; "unres," unrestricted permuation.