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Archived Comments for: Consistent Differential Expression Pattern (CDEP) on microarray to identify genes related to metastatic behavior

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  1. POSTN expression confirmed by Nature paper

    Jim Zheng, Medical University of South Carolina

    14 February 2012

    POSTN is a consistently differentially expressed gene identified by CDEP. Now it has been shown that POSTN is a stromal niche component that is induced on metastasis formation

    Malanchi I, Santamaria-Martínez A, Susanto E, Peng H, Lehr HA, Delaloye JF, Huelsken J.
    Interactions between cancer stem cells and their niche govern metastatic colonization. Nature. 2011 Dec 7;481(7379):85-9.
    doi:10.1038/nature10694. PubMed PMID: 22158103.

    Competing interests

    Corresponding author of CDEP paper