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Table 12 TC scores for different weights of relative solvent accessibility on the SABmark benchmark. Bold denotes the two best scores, and an extra superscript of star denotes the highest score.

From: MSACompro: protein multiple sequence alignment using predicted secondary structure, solvent accessibility, and residue-residue contacts

w3 0 0.1 0.2 0.3 0.4 0.5 0.6 0.7 0.8 0.9 1
TC 39.948 41.300 43.035 43.943 44.870 45.442 * 45.184 45.031 44.0383 42.4471 41.012
  1. The results show that using relative solvent accessibility information (i.e. w3 > 0) always increases the alignment scores over without using it (i.e. w3 = 0). MSACompro yielded the highest accuracy score of ~68.70 when w2 is set to 0.5.