Figure 1
From: MotifMap: integrative genome-wide maps of regulatory motif sites for model species
Explanation of methods. Diagram of updated methods. The reference genome is searched to find candidate sites and compute NLOD scores. Using the sequence around each site, overlapping aligned blocks of sequence are extracted from the multiple alignment. Nearby blocks are merged and then the best motif binding site in each species is found. The scores of the best motif sequences for each species are used to compute the BBLS score.