Figure 6
From: Estimating developmental states of tumors and normal tissues using a linear time-ordered model
Temporal distributions of mouse normal liver tissues and tumors. (A) Projection positions of mouse fetal liver development time-course samples on the Cell developmental state line based on dataset GSE 13149. The sample 11.5 d was set as the origin point; other projection positions were normalized by sample 11.5 d. (B) Distributions of projection positions of mouse liver samples treated with carcinogens from dataset GSE 5128. Green represents normal mouse liver samples. Yellow represents liver samples from mice fed negative carcinogens. Red represents liver samples from mice fed with positive carcinogen for 13 weeks. (C) Distributions of projection positions of mouse HCC samples and normal WT liver samples based on dataset GSE9012. Green represents normal WT mouse liver samples. Red represents mouse HCC samples.