Figure 3

Sequence patterns and prediction performance of O-GlcNAcylation sites. Above, Graphical representation of sequence patterns surrounding the O-GlcNAcylation sites as determined by Two Sample Logo. The height of the amino acid character represents the relative frequency (enrichment or depletion) of the amino acid at any given positions relative to the O-GlcNAcylated residue (S/T at position "0"). Below, An ROC curve of OGlcNAcScan obtained in a five-fold cross-validation test. The area under this curve (i.e., AUC) is 74.3% of the plot area. The diagonal line indicates the ROC curve of random guessing, where the corresponding AUC value is 50%.