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Table 2 Major GO categories of human O-GlcNAcylated proteins.

From: dbOGAP - An Integrated Bioinformatics Resource for Protein O-GlcNAcylation

Gene Ontology (GO) Terms

Count*

% Total

P-Value

GO Biological Processes

   

GO:0045449~regulation of transcription

108

23.48

5.90E-04

GO:0006350~transcription

93

20.22

1.99E-04

GO:0051252~regulation of RNA metabolic process

75

16.30

6.09E-03

GO:0006355~regulation of transcription, DNA-dependent

69

15.00

3.08E-02

GO:0043933~macromolecular complex subunit organization

54

11.74

1.64E-09

GO:0065003~macromolecular complex assembly

53

11.52

4.68E-10

GO:0046907~intracellular transport

52

11.30

8.96E-10

GO:0007049~cell cycle

52

11.30

2.14E-07

GO:0006412~translation

51

11.09

3.30E-21

GO:0006396~RNA processing

51

11.09

4.00E-12

GO:0008104~protein localization

51

11.09

1.91E-05

GO:0010605~negative regulation of macromolecule metabolic process

48

10.43

1.39E-06

GO:0042981~regulation of apoptosis

48

10.43

1.60E-05

GO:0043067~regulation of programmed cell death

48

10.43

2.07E-05

GO:0010941~regulation of cell death

48

10.43

2.25E-05

GO:0045184~establishment of protein localization

47

10.22

1.11E-05

GO:0010604~positive regulation of macromolecule metabolic process

47

10.22

1.55E-04

GO Molecular Function

   

GO:0000166~nucleotide binding

132

28.70

2.56E-13

GO:0003677~DNA binding

101

21.96

7.11E-04

GO:0032555~purine ribonucleotide binding

92

20.00

7.02E-06

GO:0032553~ribonucleotide binding

92

20.00

7.02E-06

GO:0017076~purine nucleotide binding

92

20.00

3.91E-05

GO:0030528~transcription regulator activity

83

18.04

6.87E-07

GO:0003723~RNA binding

82

17.83

2.05E-24

GO:0001882~nucleoside binding

82

17.83

1.56E-05

GO:0005524~ATP binding

81

17.61

1.03E-06

GO:0032559~adenyl ribonucleotide binding

81

17.61

1.73E-06

GO:0030554~adenyl nucleotide binding

81

17.61

1.26E-05

GO:0001883~purine nucleoside binding

81

17.61

2.16E-05

GO:0005198~structural molecule activity

56

12.17

8.96E-12

GO:0042802~identical protein binding

51

11.09

3.27E-09

GO Cellular Component

   

GO:0043232~intracellular non-membrane-bounded organelle

170

36.96

6.37E-29

GO:0043228~non-membrane-bounded organelle

170

36.96

6.37E-29

GO:0005829~cytosol

141

30.65

7.16E-46

GO:0031974~membrane-enclosed lumen

131

28.48

6.60E-24

GO:0043233~organelle lumen

129

28.04

1.20E-23

GO:0070013~intracellular organelle lumen

128

27.83

5.00E-24

GO:0031981~nuclear lumen

116

25.22

2.44E-25

GO:0005856~cytoskeleton

77

16.74

2.21E-08

GO:0005654~nucleoplasm

77

16.74

2.07E-18

GO:0030529~ribonucleoprotein complex

72

15.65

3.55E-29

GO:0005730~nucleolus

55

11.96

3.09E-11

GO:0000267~cell fraction

49

10.65

2.01E-03

GO:0044430~cytoskeletal part

49

10.65

1.16E-04

  1. * The table is sorted based on counts of proteins annotated with given GO terms in each of the major GO category. The percentage of proteins with given GO terms over total number of human O-GlcNAcylated proteins is shown (% Total). A more detailed GO profiles are shown in [Additional file 1, Supplementary Table S1].