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Table 2 Seventeen significant pathways (P <= 0.01) discovered in both European-American and African-American ancestry samples of schizophrenia

From: SNP-based pathway enrichment analysis for genome-wide association studies

PATHWAYS   European Ancestry (EA) African Ancestry (AA)
   Nom P GENE SIZE SNP SIZE Nom P GENE SIZE SNP SIZE
HSA04720 Long-term potentiation 0.001 67 66 <0.001 69 135
HSA04270 Vascular smooth muscle contraction <0.001 107 105 <0.001 113 215
HSA05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) <0.001 72 135 <0.001 74 144
HSA04020 Calcium signaling pathway <0.001 168 165 <0.001 174 337
HSA04972 Pancreatic secretion 0.008 93 91 <0.001 94 184
HSA04360 Axon guidance <0.001 122 120 <0.001 126 245
HSA04080 Neuroactive ligand-receptor interaction <0.001 256 248 <0.001 266 509
HSA04510 Focal adhesion <0.001 186 186 <0.001 191 378
HSA04730 Long-term depression <0.001 68 129 0.001 68 134
HSA00330 Arginine and proline metabolism 0.001 47 47 0.002 52 102
HSA04970 Salivary secretion 0.003 80 151 0.002 86 166
HSA05146 Amoebiasis 0.009 100 99 0.003 103 199
HSA05414 Dilated cardiomyopathy <0.001 88 86 0.005 90 173
HSA04070 Phosphatidylinositol signaling system 0.002 75 74 0.006 77 150
HSA04512 ECM-receptor interaction 0.001 81 81 0.007 82 161
HSA04260 Cardiac muscle contraction 0.009 63 61 0.009 67 128
HSA04540 Gap junction 0.003 80 80 0.009 85 165