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Table 3 Preferred Amino Acids at N terminus of helix

From: Characterization and sequence prediction of structural variations in α-helix

Subclass

N 1

N 2

N 3

N 4

Regular α-helix

S/T/D/N

P

E

E/Q

Extended Helix

D/N

P/A/W/E/L

E/A/Q

E/L/F/Q

Helix with c-cap

D/E/A

Q/A/E

E/W/A/L

L/F/I/M

Kinked helix

P/E

E/P/D

N/H/Y/F

W/A/L/F

Curved Helix

Y/F/W

E/K/R

H/N/Q/K/E

N/D/H/C/G

  1. We have listed the most preferred amino acids at N-terminus positions in the helix. At each position, the amino acids are arranged in descending order of their propensities. The positions in the N-terminus are denoted by N1 to N4 from left to right.