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Table 4 Preferred Amino Acids at C terminus of helix

From: Characterization and sequence prediction of structural variations in α-helix

Subclass

C 4

C 3

C 2

C 1

Regular α-helix

A/I/L

K/A/R/E/Q

L/A/Q/K/R

G

Extended Helix

L/M/A

L/Q/K

L/Q/K

L/F/Y/Q/M

Helix with c-cap

L/A/R/M

K/ R/ E/ Q/ L

H/ Y/ F

G

Kinked helix

P

E/Q/W

L/I/F/Y/V

L/M/I/A

Curved Helix

P

P/E

H/P/W

F/Y/L/W/A

  1. We have listed the most preferred amino acids at C-terminus positions in the helix. At each position, the amino acids are arranged in descending order of their propensities. The position in the C-terminus are denoted by C1 to C4 from right to left.