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Table 4 Pathways over-represented in genes with SNPs modifying splicing

From: Genome-wide prediction of splice-modifying SNPs in human genes using a new analysis pipeline called AASsites

Pathway

Count

%

P-Value

Focal adhesion

30

3.5

5.9E-6

ECM-receptor interaction

17

2.0

5.7E-5

Metabolism of xenobiotics by cytochrome P450

12

1.4

2.3E-3

ABC transporters - General

9

1.1

4.9E-3

Bladder cancer

7

0.8

3.1E-2

Regulation of actin cytoskeleton

21

2.5

3.3E-2

Adherens junction

10

1.2

3.3E-2

Phenylpropanoid biosynthesis

3

0.4

6.3E-2

Colorectal cancer

10

1.2

7.0E-2

Small cell lung cancer

10

1.2

7.8E-2

Cyanoamino acid metabolism

3

0.4

8.0E-2

Non-small cell lung cancer

7

0.8

9.2E-2

Pathogenic Escherichia coli infection - EPEC

7

0.8

9.8E-2

  1. The overexpressed pathways are shown together with the number of genes involved in the pathway (Count), the percentage of genes involved in the pathway compared to all input genes (%), and the p value from the Fisher test calculated by the DAVID tool.