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Table 4 Pathways over-represented in genes with SNPs modifying splicing

From: Genome-wide prediction of splice-modifying SNPs in human genes using a new analysis pipeline called AASsites

Pathway Count % P-Value
Focal adhesion 30 3.5 5.9E-6
ECM-receptor interaction 17 2.0 5.7E-5
Metabolism of xenobiotics by cytochrome P450 12 1.4 2.3E-3
ABC transporters - General 9 1.1 4.9E-3
Bladder cancer 7 0.8 3.1E-2
Regulation of actin cytoskeleton 21 2.5 3.3E-2
Adherens junction 10 1.2 3.3E-2
Phenylpropanoid biosynthesis 3 0.4 6.3E-2
Colorectal cancer 10 1.2 7.0E-2
Small cell lung cancer 10 1.2 7.8E-2
Cyanoamino acid metabolism 3 0.4 8.0E-2
Non-small cell lung cancer 7 0.8 9.2E-2
Pathogenic Escherichia coli infection - EPEC 7 0.8 9.8E-2
  1. The overexpressed pathways are shown together with the number of genes involved in the pathway (Count), the percentage of genes involved in the pathway compared to all input genes (%), and the p value from the Fisher test calculated by the DAVID tool.