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Table 2 Our SADI services based on the Mutation Impact ontology, text-mining pipeline and database. Detailed information (in RDF) about a service can be obtained by opening the service URL, obtained by attaching the prefix http://unbsj.biordf.net/mi-sadi/ to the name, in a Web browser.

From: Deploying mutation impact text-mining software with the SADI Semantic Web Services framework

service

operation

mineTextForMutationImpacts

extracts mutation specifications from a document

getMutationByWildtypeProtein

finds specifications of mutations grounded to a given protein

getMutationByMutantProtein

finds specifications of mutations resulting in a protein specified by its sequence

getMutationImpactByProteinProperty

finds mutation impact instances affecting a specified grounded protein property

getMutationByImpact

finds mutation specifications corresponding to an impact on a specified grounded protein property

getMutationSubseries

finds mutation series instances that are subseries of a given mutation series

getMIDBBioEntityByType

finds biological entities by their type URIs

getProteinPropertyByType

finds protein properties grounded to specific proteins by their type URIs

visualiseMutationSeries

renders the 3D structure of the wildtype protein, from PDB, and highlights the point mutation positions

visualiseMutationSeriesWithHomologyModeling

same as visualiseMutationSeries except that the 3D structure is predicted by homology modeling