Power of detecting medium-size deletions at low to moderate depth of coverage. The blue and red dashed lines are theoretical values using 1.5kbp and 200bp insert libraries, respectively. The green and purple solid lines are results from Zinfandel on the simulated data with 1.5kbp and 200bp insert libraries, respectively. The standard deviation of 1.5kbp- and 200bp- inserts was set at 200 and 20, respectively, based on empirical data from Life SOLiDTM and Illumina SolexaTM platforms . The black and gray lines are results from BreakDancer on the simulated data, and the brown dashed lines are theoretical values for methods solely based on depth of coverage.