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Figure 1 | BMC Bioinformatics

Figure 1

From: Towards the identification of protein complexes and functional modules by integrating PPI network and gene expression data

Figure 1

A framework for detecting protein complex and functional modules based on the combination of a PPI network and time-sequenced gene expressions. Clustering method 1 is used for predicting protein complexes while clustering method 2 is used for mining functional modules according to the identified complexes. In this framework, each previous clustering algorithm can be used as a candidate of clustering method 1 for identifying protein complexes as well as clustering method 2 for identifying functional modules.

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