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Table 2 Functional enrichments of the identified complexes detected by TSN-PCD and functional modules detected by DFM-CIN, MCL, MCODE, CPM, SPICI, and COACH

From: Towards the identification of protein complexes and functional modules by integrating PPI network and gene expression data

 

Number of

Average

% of significant

Average

Significant modules(P)

Algorithms

modules

size

modules

(-logP)

<E-15

E-15 to E-10

E-10 to E-5

E-5 to 0.001

TSN-PCD

865

26.41

95.95

16.36

39.77%(344)

19.65%(170)

26.24%(227)

10.29%(89)

DFM-CIN

280

18.28

92.14

14.49

30.71%(86)

13.93%(39)

34.64%(97)

12.86%(36)

MCL

619

6.58

59.93

5.07

4.2%(26)

5.00%(31)

20.52%(127)

30.21%(187)

MCODE

50

15.66

92.00

8.53

12.00%(6)

12.00%(6)

50.00%(25)

18.00%(9)

CPM

126

11.59

92.65

11.14

20.63%(26)

14.28%(18)

38.89%(49)

19.84%(25)

SPICI

552

11.59

66.85

5.00

4.71%(26)

3.80%(21)

21.19%(117)

37.14%(205)

COACH

894

8.99

85.57

7.76

10.85%(97)

11.97%(107)

35.79%(320)

26.96%(241)