Figure 3
From: Detection and correction of probe-level artefacts on microarrays
Boxplot of the log 2 fold changes for probesets with 0, 1, 2, 3 or 4 spiked probes in the simulation in which 5% of all probes were spiked in total ( δ =0.05). Here, probesets with the same number of spiked probes were pooled across all simulation results. For the case of 0 spiked probes, probesets were selected randomly from the pooled set as there were too many probesets for loading into R. In this case, each probeset was selected with a probability of 0.01. We observe a very strong correlation between the number of affected probes and fold-change biases on probeset level, which may seriously harm downstream analyses.