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Table 2 Most important edge types in Biomine

From: Biomine: predicting links between biological entities using network models of heterogeneous databases

Edge type

Source databases

Count

Protein is associated to Protein

STRING

2,916,000

Article refers to Node

Entrez Gene, UniProt, KEGG, OMIM

2,250,000

Node has annotation GO

Entrez Gene, UniProt, InterPro

1,365,000

Protein contains Feature

UniProt

507,000

Gene is homologous to Gene

HomoloGene

259,000

Gene codes for Protein

Entrez Gene, STRING

174,000

Gene is located in Locus

Entrez Gene, OMIM

151,000

Protein belongs to Family

UniProt

114,000

Protein interacts with Protein

Entrez Gene, UniProt

98,000

OMIM refers to OMIM

OMIM

85,000

Gene participates in Pathway

KEGG

65,000

GO has parent GO

GO

56,000

InterPro has parent InterPro

InterPro

20,000

Compound participates in Pathway

KEGG

9,700

Gene affects Phenotype

Entrez Gene

5,100

Phenotype is mapped to Locus

OMIM

3,400

  

total 8,078,000

  1. “Node” denotes any type of node, “OMIM” denotes nodes of type “Gene”, “Gene variant” or “Phenotype”, “GO” denotes nodes of type “Molecular function”, “Cellular component” or “Biological process“, and “InterPro” denotes nodes of type “Protein family” or “Protein feature”. Edge types with less than 3,000 instances are not listed.