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Table 2 Confident "driver" genes for breast cancer metastasis

From: Core module biomarker identification with network exploration for breast cancer metastasis

Symbol Entrez Description
MAP2K1 [32] 5604 mitogen-activated protein kinase kinase 1
E2F1 [14] 1869 E2F transcription factor 1
GRB2 [33] 2885 growth factor receptor-bound protein 2
NFKB1 [34] 4790 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
RB1 [35] 5925 retinoblastoma 1
BRCA1 [36] 672 breast cancer 1, early onset
FOS [37] 2353 v-fos FBJ murine osteosarcoma viral oncogene homolog
SOS1 [38] 6654 son of sevenless homolog 1 (Drosophila)
PIK3CA [39] 5290 phosphoinositide-3-kinase, catalytic, alpha polypeptide
JAK1 [40] 3716 Janus kinase 1
SHC1 [41] 6464 SHC (Src homology 2 domain containing) transforming protein 1
MYC [42] 4609 v-myc myelocytomatosis viral oncogene homolog (avian)
CCNA2 [37] 890 cyclin A2