Table 9 The top 5 enriched GO terms for each dysregulated pathway in pancreatic tumour (GSE16515) dataset
From: Identifying dysregulated pathways in cancers from pathway interaction networks
Pathway | GO: term | p-value | Term name |
|---|---|---|---|
KEGG_P53_SIGNALING_PATHWAY | GO:0051726 | 1.30E-33 | regulation of cell cycle |
GO:0006917 | 1.30E-22 | induction of apoptosis | |
GO:0012502 | 1.50E-22 | induction of programmed cell death | |
GO:0006915 | 1.10E-20 | apoptosis | |
GO:0042981 | 1.20E-20 | regulation of apoptosis | |
ST_JNK_MAPK_PATHWAY | GO:0000165 | 6.70E-33 | MAPKKK cascade |
GO:0023014 | 8.90E-27 | signal transmission via phosphorylation event | |
GO:0007243 | 8.90E-27 | intracellular protein kinase cascade | |
GO:0031098 | 1.40E-23 | stress-activated protein kinase signaling cascade | |
GO:0007254 | 8.60E-22 | JNK cascade | |
ST_P38_MAPK_PATHWAY | GO:0044087 | 1.40E-13 | regulation of cellular component biogenesis |
GO:0043254 | 4.70E-13 | regulation of protein complex assembly | |
GO:0030833 | 3.30E-12 | regulation of actin filament polymerization | |
GO:0030036 | 4.40E-12 | actin cytoskeleton organization | |
GO:0008064 | 6.40E-12 | regulation of actin polymerization or depolymerization | |
BIOCARTA_SALMONELLA_PATHWAY | GO:0006793 | 1.70E-17 | phosphorus metabolic process |
GO:0006796 | 1.70E-17 | phosphate metabolic process | |
GO:0006468 | 4.10E-17 | protein amino acid phosphorylation | |
GO:0016310 | 1.30E-16 | phosphorylation | |
GO:0043687 | 9.20E-16 | post-translational protein modification | |
BIOCARTA_CDC42RAC_PATHWAY | GO:0044087 | 1.20E-14 | regulation of cellular component biogenesis |
GO:0043254 | 3.10E-12 | regulation of protein complex assembly | |
GO:0032956 | 3.30E-12 | regulation of actin cytoskeleton organization | |
GO:0032970 | 4.20E-12 | regulation of actin filament-based process | |
GO:0030833 | 1.50E-11 | regulation of actin filament polymerization |