Table 1 ROCS results for the number of Experimental Replicates and Prey Proteins as a function of procedural stages from the initial “Naïve” stage (“ N ”), to the “Reproducible” stage (“ R ”), and to the final “Specific” stage (“ S ”) for all the AP-MS bait experiments: VHL, CTNNBIP1, NME2, PPM1B, and STK24

Stages

Stage “N”

Stage “R”

Stage “S”

Bait Experiment

Experimental Replicates

$\left({\mathit{K}}^{\mathit{B}}\right)$

Prey Proteins

$\left({\mathit{N}}^B\right)$

Reproducible Experimental Replicates

$\left({\widehat{\mathit{L}}}^{\mathit{B}}\left({\tilde{\mathit{p}}}_{\mathit{min}}^{\mathit{B}}\right)\right)$

Reproducible Prey Proteins

$\left({\mathit{R}}^{\mathit{B}}\left({\tilde{\mathit{p}}}_{\mathit{min}}^{\mathit{B}}\right)\right)$

Reproducible Experimental Replicates

$\left({\widehat{\mathit{L}}}^{\mathit{B}}\left({\tilde{\mathit{p}}}_{\mathit{min}}^{\mathit{B}}\right)\right)$

Specific Prey Proteins

$\left({\mathit{S}}^{\mathit{B}}({\tilde{\mathit{p}}}_{\mathit{min}}^{\mathit{B}},{\tilde{\mathit{p}}}_{\mathit{min}}^{\mathit{C}},{\mathit{C}}_{\mathit{S}}^{\mathit{cutoff}})\right)$

$\left({\widehat{\mathit{C}}}_{\mathit{S}}^{\mathit{cutoff}}\right)$