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Figure 2 | BMC Bioinformatics

Figure 2

From: Simulating gene-gene and gene-environment interactions in complex diseases: Gene-Environment iNteraction Simulator 2

Figure 2

Example of application of epistasis. Disease penetrance for combined genotypes before (left panel) and after (right panel) the application of an epistasis model with an increment of 20% of the risk associated with the (CC-TT) composed genotype. The x- and y- axes plot the reported genotypes of the two DPLs; the z-axis plots the risk associated with each combined genotype.

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BMC Bioinformatics

ISSN: 1471-2105

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