Pathway type | Statistic | GSEA | GSA | PADOG |
---|
Target | p med |
0.2603
|
0.087
|
0.043
|
Target | rank med | 39.56 |
10.15
|
6.42
|
Apoptosis | p med | 0.3329 | 0.203 | 0.1985 |
Apoptosis | rank med |
37.56
| 24.24 | 28.76 |
Cell cycle | p med |
0.3133
| 0.325 | 0.227 |
Cell cycle | rank med |
26.29
| 36.35 | 28.61 |
Pathways in cancer | p med | 0.351 |
0.114
|
0.0465
|
Pathways in cancer | rank med | 47.54 |
13.21
|
8.41
|
RNA polymerase | p med | 0.5 | 0.681 | 0.6485 |
RNA polymerase | rank med | 57.78 | 71.51 | 63.33 |
- The table shows a comparison between the pathways specifically designed by KEGG for each type of cancer (Target pathways) and other pathways that are commonly involved in many cancers. The table shows statistics computed from nominal p-values, and ranks of each type of pathway for the 16 cancer datasets shown in Table 1. PADOG gives the most significant p-values and best ranks to the target pathways. For each analysis method, the values for type of pathway with the smallest median p-values and ranks (strongest association with the phenotype) are shown in bold, while the second smallest values are italicized.