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Table 2 Significantly enriched GO terms

From: Developing a powerful In Silico tool for the discovery of novel caspase-3 substrates: a preliminary screening of the human proteome

GO ID GO Term P-value Term in predicted proteins Term in human genome
GO:0007155 cell adhesion 1.02E-39 322 885
GO:0022008 neurogenesis 3.97E-27 324 1016
GO:0007049 cell cycle 2.71E-26 376 1250
GO:0030030 cell projection organization 6.53E-26 263 776
GO:0009966 regulation of signal transduction 6.37E-23 399 1399
GO:0007010 cytoskeleton organization 9.69E-21 217 641
GO:0051276 chromosome organization 8.07E-20 212 630
GO:0000902 cell morphogenesis 1.35E-19 228 698
GO:0040011 locomotion 4.84E-18 310 1071
GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 6.98E-16 227 737
GO:0009790 embryo development 9.49E-15 245 830
  1. The GO terms of the listed biological processes were manually filtered, to reduce redundancy, by removing general roots (parents) and detailed leaves (children) of the enriched GO terms that were obtained by ToppFun tool. The P-value of each GO term in the predicted caspase-3 proteins was derived by random sampling of the whole genome.