Table 5 Detailed Results of DoBi, metaPPI, meta-PPISP and PPI-Pred on 41 complexes
From: Protein-protein binding site identification by enumerating the configurations
Complex | Protein 1 | Protein 2 | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
PDBa | Int n b | DoBi | metaPPIf | meta-PPISPf | PPI-Predg | PDB | Int n | DoBi | metaPPI | meta-PPISP | PPI-Pred | |||||||||
Acc c | Cov d | Acc | Cov | Acc | Cov | Acc | Cov | Acc | Cov | Acc | Cov | Acc | Cov | Acc | Cov | |||||
E-Ie | ||||||||||||||||||||
1acb(E:I)h | 2cgaB | 24 | 33.3 | 20.8 | 87.5 | 56.0 | 60.7 | 68.0 | 76.0 | 79.2 | 1egl_ | 13 | 63.2 | 92.3 | 66.7 | 58.8 | 100 | 53.6 | 90.0 | 69.2 |
1ay7(A:B) | 1rghB | 15 | 75.0 | 100 | 27.3 | 17.6 | 53.8 | 33.3 | 0 | 0 | 1a19B | 15 | 60.0 | 80.0 | 72.7 | 53.3 | 92.9 | 81.2 | 0 | 0 |
1cgi(E:I) | 2cgaB | 33 | 64.3 | 27.3 | 100 | 55.2 | 56.0 | 48.2 | 96.2 | 75.8 | 1hpt_ | 19 | 93.3 | 73.7 | 100 | 36.8 | 89.5 | 77.3 | 100 | 63.2 |
1d6r(A:I) | 2tgt_ | 27 | 43.8 | 25.9 | 54.5 | 28.6 | 53.6 | 71.4 | 73.9 | 63.0 | 1k9bA | 13 | 66.7 | 92.3 | 44.4 | 53.3 | 35.7 | 15.2 | 22.2 | 15.4 |
1dfj(E:I) | 9rsaB | 29 | 41.0 | 55.2 | 64.3 | 26.5 | 57.7 | 48.4 | 55.0 | 37.9 | 2bnh_ | 33 | 43.5 | 60.6 | 81.3 | 31.0 | 32.4 | 91.7 | 21.3 | 30.3 |
1e6e(A:B) | 1e1nA | 20 | 42.3 | 55.0 | 0 | 0 | 26.9 | 43.8 | 14.9 | 55.0 | 1cjeD | 23 | 65.2 | 65.2 | 93.3 | 50.0 | 79.2 | 73.1 | 15.4 | 17.4 |
1eaw(A:B) | 1eaxA | 22 | 21.1 | 18.2 | 100 | 48.0 | 46.8 | 60.0 | 66.7 | 72.7 | 9pti_ | 14 | 52.6 | 71.4 | 100 | 42.9 | 95.0 | 79.2 | 8.3 | 7.1 |
1ewy(A:C) | 1gjrA | 19 | 57.1 | 84.2 | 9.1 | 5.3 | 5.6 | 8.3 | 16.7 | 52.6 | 1czpA | 17 | 51.6 | 94.1 | 57.1 | 42.1 | 63.2 | 63.2 | 50.0 | 41.2 |
1f34(A:B) | 4pep_ | 25 | 44.8 | 52.0 | 30.8 | 12.5 | 30.3 | 52.6 | 47.5 | 76.0 | 1f32A | 24 | 57.9 | 45.8 | 72.7 | 24.2 | 55.2 | 69.6 | 70.4 | 79.2 |
1mah(A:F) | 1j06B | 27 | 35.9 | 51.9 | 16.7 | 3.4 | 28.0 | 63.6 | 36.6 | 96.3 | 1fsc_ | 21 | 86.4 | 90.5 | 15.8 | 15.0 | 33.3 | 21.9 | 33.3 | 28.6 |
1ppe(E:I) | 1btp_ | 27 | 64.9 | 88.9 | 64.3 | 42.9 | 40.9 | 42.8 | 0 | 0 | 1lu0A | 14 | 63.2 | 85.7 | 92.3 | 75.0 | 100 | 56.0 | 90.0 | 64.3 |
1tmq(A:B) | 1jae_ | 28 | 62.2 | 82.1 | 75.0 | 40.0 | 36.0 | 30.0 | 63.4 | 92.9 | 1b1uA | 26 | 57.1 | 76.9 | 93.3 | 56.0 | 70.4 | 76.0 | 0 | 0 |
1udi(E:I) | 1udh_ | 26 | 52.2 | 46.2 | 63.6 | 25.9 | 48.0 | 66.7 | 72.0 | 69.2 | 2ugiB | 26 | 94.4 | 65.4 | 92.9 | 56.5 | 72.7 | 80.0 | 85.7 | 46.2 |
2pcc(A:B) | 1ccp_ | 13 | 20.0 | 23.1 | 53.8 | 50.0 | 26.7 | 33.3 | 0 | 0 | 1ycc_ | 14 | 26.3 | 35.7 | 42.9 | 35.3 | 37.5 | 33.3 | 13.3 | 14.3 |
2sic(E:I) | 1sup_ | 26 | 50.0 | 46.2 | 72.7 | 38.1 | 81.8 | 60.0 | 62.5 | 76.9 | 3ssi_ | 12 | 84.6 | 91.7 | 0 | 0 | 100 | 72.2 | 0 | 0 |
2sni(E:I) | 1ubnA | 27 | 66.7 | 59.3 | 60.0 | 33.3 | 60.0 | 83.0 | 66.7 | 81.5 | 2ci2I | 15 | 42.9 | 40.0 | 57.1 | 57.1 | 0 | 0 | 76.9 | 66.7 |
7cei(A:B) | 1unkD | 20 | 76.9 | 50.0 | 75.0 | 35.3 | 47.4 | 60.0 | 75.0 | 45.0 | 1m08B | 16 | 64.3 | 56.3 | 40.0 | 37.5 | 0 | 0 | 13.8 | 25.0 |
others | ||||||||||||||||||||
1ak4(A:D) | 2cpl_ | 17 | 42.9 | 35.3 | 50.0 | 31.3 | 33.3 | 18.8 | 59.1 | 76.5 | 1e6jP | 9 | 30.4 | 77.8 | 0 | 0 | 0 | 0 | 0 | 0 |
1atn(A:D) | 1ijjB | 17 | 5.3 | 5.9 | 0 | 0 | 20.7 | 37.5 | 0 | 0 | 3dni_ | 24 | 40.0 | 33.3 | 0 | 0 | 0 | 0 | 66.7 | 66.7 |
1b6c(A:B) | 1d6oA | 20 | 54.3 | 95.0 | 83.3 | 55.6 | 40.0 | 11.1 | 93.3 | 70.0 | 1iasA | 20 | 44.0 | 55.0 | 54.5 | 25.0 | 31.6 | 25.0 | 0 | 0 |
1buh(A:B) | 1hcl_ | 16 | 68.4 | 81.3 | 0 | 0 | 6.3 | 11.8 | 0 | 0 | 1dksA | 18 | 75.0 | 83.3 | 58.3 | 38.9 | 36.4 | 22.2 | 100 | 66.7 |
1e96(A:B) | 1mh1_ | 14 | 66.7 | 85.7 | 38.5 | 25.0 | 46.2 | 60.0 | 10.0 | 14.3 | 1hh8A | 12 | 73.3 | 91.7 | 41.7 | 35.7 | 45.5 | 35.7 | 0 | 0 |
1fq1(A:B) | 1fpzF | 16 | 63.2 | 75.0 | 0 | 0 | 0 | 0 | 0 | 0 | 1b39A | 16 | 63.2 | 75.0 | 0 | 0 | 30.0 | 23.1 | 17.1 | 37.5 |
1fqj(A:B) | 1tndC | 21 | 20.7 | 81.0 | 70.6 | 42.9 | 32.3 | 35.7 | 28.6 | 38.1 | 1fqiA | 24 | 18.9 | 58.3 | 90.9 | 47.6 | 42.9 | 14.3 | 78.9 | 62.5 |
1gcq(B:C) | 1griB | 14 | 35.3 | 42.9 | 70.0 | 63.6 | 38.9 | 63.6 | 22.2 | 14.3 | 1gcpB | 18 | 78.9 | 83.3 | 60.0 | 40.0 | 100 | 33.3 | 33.3 | 16.7 |
1ghq(A:B) | 1c3d_ | 10 | 41.7 | 100 | 0 | 0 | 42.9 | 37.5 | 0 | 0 | 1ly2A | 9 | 47.4 | 100 | 0 | 0 | 42.9 | 66.7 | 8.7 | 22.2 |
1grn(A:B) | 1a4rA | 17 | 54.2 | 76.5 | 33.3 | 15.0 | 40.0 | 40.0 | 50.0 | 58.8 | 1rgp_ | 22 | 50.0 | 54.5 | 16.7 | 4.5 | 100 | 13.6 | 78.9 | 68.2 |
1h1v(A:G) | 1ijjB | 24 | 28.6 | 41.7 | 46.2 | 13.0 | 35.3 | 26.1 | 38.8 | 76.0 | 1d0nB | 25 | 43.8 | 56.0 | 0 | 0 | 40.0 | 4.9 | 4.7 | 12.0 |
1he1(C:A) | 1mh1_ | 16 | 48.0 | 75.0 | 66.7 | 30.8 | 50.0 | 42.3 | 0 | 0 | 1he9A | 21 | 40.9 | 42.9 | 76.5 | 46.4 | 33.3 | 7.1 | 0 | 0 |
1he8(B:A) | 821P_ | 13 | 20.6 | 100 | 0 | 0 | 43.8 | 33.3 | 26.7 | 61.5 | 1e8zA | 15 | 11.1 | 53.3 | 42.9 | 16.7 | 5.9 | 5.6 | 0.6 | 6.7 |
1i2m(A:B) | 1qg4A | 24 | 14.3 | 33.3 | 42.9 | 21.4 | 43.8 | 50.0 | 15.0 | 12.5 | 1a12A | 32 | 15.1 | 43.8 | 0 | 0 | 50.0 | 5.1 | 48.0 | 75.0 |
1ibr(A:B) | 1qg4A | 35 | 43.2 | 45.7 | 73.3 | 22.0 | 55.0 | 22.0 | 14.3 | 8.6 | 1f59A | 42 | 38.9 | 33.3 | 7.1 | 1.8 | 0 | 0 | 10.3 | 16.7 |
1kac(A:B) | 1nobF | 15 | 68.4 | 86.7 | 0 | 0 | 15.4 | 21.1 | 0 | 0 | 1f5wB | 21 | 83.3 | 95.2 | 60.0 | 28.6 | 71.4 | 23.8 | 35.3 | 28.6 |
1ktz(A:B) | 1tgk_ | 9 | 26.7 | 44.4 | 45.5 | 62.5 | 13.3 | 25.0 | 50.0 | 88.9 | 1m9zA | 12 | 57.1 | 100 | 66.7 | 80.0 | 60.0 | 60.0 | 33.3 | 50.0 |
1kxp(A:D) | 1ijjB | 34 | 13.6 | 8.8 | 81.3 | 30.2 | 45.5 | 23.3 | 4.3 | 5.9 | 1kw2B | 41 | 32.0 | 19.5 | 0 | 0 | 75.0 | 13.0 | 48.9 | 56.1 |
1kxq(H:A) | 1kxqH | 25 | 12.1 | 16.0 | 91.7 | 30.6 | 78.6 | 30.6 | 18.2 | 8.0 | 1ppi_ | 30 | 22.7 | 16.7 | 41.7 | 17.9 | 20.0 | 3.6 | 47.8 | 73.3 |
1m10(A:B) | 1auq_ | 24 | 57.1 | 50.0 | 58.3 | 24.1 | 65.0 | 44.8 | 50.0 | 45.8 | 1mozB | 29 | 68.0 | 58.6 | 0 | 0 | 31.6 | 18.2 | 0 | 0 |
1qa9(A:B) | 1hnf_ | 16 | 76.2 | 100 | 0 | 0 | 27.3 | 17.6 | 10.0 | 12.5 | 1cczA | 16 | 82.4 | 87.5 | 6.7 | 5.3 | 22.2 | 10.5 | 28.6 | 25.0 |
1sbb(A:B) | 1bec_ | 13 | 54.2 | 100 | 0 | 0 | 17.6 | 17.6 | 0 | 0 | 1se4_ | 11 | 50.0 | 100 | 0 | 0 | 50.0 | 12.5 | 10.0 | 27.3 |
1wq1(R:G) | 6q21D | 26 | 61.5 | 61.5 | 66.7 | 32.3 | 41.7 | 32.2 | 76.2 | 61.5 | 1wer_ | 33 | 62.5 | 45.5 | 100 | 26.5 | 36.4 | 11.8 | 70.0 | 63.6 |
2btf(A:P) | 1ijjB | 26 | 63.3 | 73.1 | 53.3 | 32.0 | 25.0 | 12.0 | 22.0 | 42.3 | 1pne_ | 23 | 56.0 | 60.9 | 0 | 0 | 70.0 | 28.0 | 0 | 0 |