Finding minimum gene subsets with heuristic breadth-first search algorithm for robust tumor classification

BMC Bioinformatics

Table 8 Top 10 genes selected by HBSA-KNN from the leukemia dataset

Top ten genes	CLD	Validation of tumor-related genes
APLP2	4	stability
CD33	3	[73, 74]
ZYX	--	Tumor suppressor
MARCKSL1		[75]
SP3	9	[76]
CD63	2	[77]; tumor suppressor
TCF3	--	[78]
PSME1	1	--
CCND3	--	Tumor suppressor
CST3	--	PMID: 17728092

The genes are sorted according to their frequency. If a gene is validated in the literature, the corresponding reference is shown (‘PMID’ denotes the PubMed ID).

ISSN: 1471-2105