A standard YAML manifest file. The manifest file contains a metadata block (name, description, category and website) and a logical block for both Cloudgene modules, including all parameters that are necessary to execute the program and from a user’s view often hard to decide. This file has to be written once and is provided to scientists. Cloudgene checks at every start up for new programs and designs the web interface dynamically to the specific scenario. Here, the submit form for CloudBurst has been generated with information from the manifest file.