Screening of selective histone deacetylase inhibitors by proteochemometric modeling

BMC Bioinformatics

Table 1 “classical” HDACs

HDAC		Localization	Chromosomal site	References
Class I (RPD3 homologue)
	HDAC1	Nucleus	1p34.1	[7]
	HDAC2	Nucleus	6p21	[8]
	HDAC3	Nucleus	5p31	[9]
	HDAC8	Nucleus	Xq13	[10]
Class II (HDA1 homologue)
IIa	HDAC4	Nuc/Cyt	2q372	[11]
	HDAC5	Nuc/Cyt	17q21	[12]
	HDAC7	Nuc/Cyt	12q13	[13]
	HDAC9	Nuc/Cyt	7p21-p15	[14]
IIb	HDAC6	Mainly Cyt	Xp11.22-33	[15]
	HDAC10	Mainly Cyt	22q13.31-33	[16]
Class IV
	HDAC11	Nuc/Cyt	3p25.2	[17]

ISSN: 1471-2105