Impact of final clustering algorithm. Jaccard similarity coefficient between reference classification SCOP and MCL (in black) or spectral clustering (in gray) automated classifications obtained with no ternary similarity constraint (dashed lines) or with a ternary similarity constraint T=0.65 (continuous lines). The vertical line at 1977 clusters (resp. 1241 clusters) gives the number of classes in SCOP (resp. with more than one protein domain).